Ces Urol 2005, 9(3):31-35 | DOI: 10.48095/cccu2005019

Effect of age, gender and ecog score on prognosis of renal carcinoma

I. Kawaciuk, L. Hyršl, P. Dušek, L. Jarolím, M. Schmidt, V. Kaliská, M. Chocholatý, M. Urbanová

Urologická klinika 2. LF UK a FN Motol, Praha

In the group of 316 patients operated for renal cell carcinoma were 191 men and 125 women (1,5 : 1). The five-year survival of men and women was 59,7% and 67,2%, respectively. The difference was not significant (p = 0,18). Distant metastasis had 14,1% men and 12% women. There were 6,3% inoperable tumors in men and only 1,6% in women. Frequency of incidental carcinomas was insignificantly higher (p = 0,24) in women (31,2 vs 25,1%). Comparison concerning TNM-classification 2002 showed higher incidence of tumors in stage I in women (36,8 vs 23%), on the contrary in men in stage IV (20,4 vs 16,8%). The difference was at the borderline of significance (p = 0,05). The average age of patients in the whole group (n = 316) was 61,5 years; 60,9 in men, 62,3 in women. The five-year survival has been decreasing more significantly from the 8th decennium. This feature is probably in coincidence with life expectancy in normal population with similar age and gender distribution.
Patients with ECOG score 0, 1 and 2 had five-year survival 76,4%, 60,2% and 40%, respectively. None of the patients with ECOG score 3 survived five years. ECOG score at the time of surgery had higher impact on survival rate in patients in stage I and II, on the contrary ECOG score had no impact on survival rate in patients in stage III and IV.

Keywords: renal cell carcinoma, prognosis, gender, age, ECOG score

Published: June 1, 2005