Ces Urol 1998, 2(3):9-13

Rare priaaary tumors of the prostate

V. Nagy, L Sokol, J. Bodnár, M. Bača, L Valanský

Urologická klinika LF UPJŠ, Košice Oddelenie patologie FNsP, Košice

The authors report 11 (3,47%) patients in the 8-to-79 age-bracket (average age 63,5) treated for an unusual or rare type of primary prostate tumor during the years 1987 - 1996. In 9 patients the rare carcinomas appeared in a mixed form with a regular adenocarcinoma of the prostate. There was a carcinoma arising from large (primary) prostate ducts diagnosed in 4 patients, urotelial carcinoma in 5 patients (1 of them in a pure form), a small-cell carcinoma in 1 patient and a pure rhabdomyosarcoma of the prostate in another 1 patient. 4 patients suffering an incidental adenocarcinoma coming out of the primary ducts have been surviving on hormonal therapy for 3 up to 73 months (49,8 months in average). The rest of the patients with advanced disease at the time of diagnosis died within 1 - 43 months in spite of combined hormonal therapy. The hormonal therapy was not successful in treating patients with rare types of prostate cancer. Surgery and radiotherapy were employed to treat brain metastases in two patients, achieving partial remission. In the discussion the authors analyse the laboratory, clinical and pathomorphological findings and look for possible deductions for the treatment.

Keywords: rare prostate tumors, ductal carcinoma, urotelial carcinoma, small-cell carcinoma, rhabdomyosarcoma of the prostate

Published: June 1, 1998