Ces Urol 2023, 27(2):70-77 | DOI: 10.48095/cccu2023008

The WHO Classification of Urinary and Male Genital Tumours 2022: renal tumours classification

Adriena Bartoš Veselá¹, Tomáš Pitra¹, Jiří Kolář¹, Josef Skopal², Ondřej Fiala³, Milan Hora¹, Ondřej Hes^2,4,†, Kristýna Pivovarčíková^{2, 4}

¹ Urologická klinika, Lékařská fakulta Plzeň, Univerzita Karlova a Fakultní nemocnice Plzeň

² Šiklův ústav patologie, Lékařská fakulta Plzeň, Univerzita Karlova a Fakultní nemocnice Plzeň

³ Onkologická a radioterapeutická klinika, Lékařská fakulta Plzeň, Univerzita Karlova a Fakultní nemocnice Plzeň a Biomedicínské centrum, Lékařská fakulta Plzeň, Univerzita Karlova

⁴ Bioptická laboratoř, s. r. o., Plzeň

^† zesnulý

Bartoš Veselá A, Pitra T, Kolář J, Skopal J, Fiala O, Hora M, Hes O, Pivovarčíková K. The WHO Classification of Urinary and Male Genital Tumours 2022: renal tumours classification. The 5th edition WHO (World Health Organization) classification of the urogenital tract tumors was published in the middle of last year (so-called blue book). The new WHO classification reflects very dynamic developments in the field of renal neoplasms (caused mainly by the more frequent implementation of molecular genetic testing into the routine diagnosis of kidney tumors), and the new WHO classification shows changes especially in the chapter on renal tumors. The new kidney tumor classification modifies some traditional entities and also redefines and includes some new kidney tumors. This review article aims to briefly outline and comment on the most significant changes in the WHO classification of renal neoplasia.

Keywords: Molecular pathology, renal cell carcinoma, renal tumours, urogenital tract, WHO 2022 classification.

Received: February 21, 2023; Revised: March 20, 2023; Accepted: March 20, 2023; Prepublished online: March 20, 2023; Published: June 16, 2023