Ces Urol 2024, 28(1):46-51 | DOI: 10.48095/cccu2024009

Nephrogenic adenoma of the bladder in renal transplant patient - case report

Kseniia Khomenko¹, Kristýna Pivovarčîková^{2, 3}, Milan Hora¹, Tomáš Pitra¹

¹ Urologická klinika, Lékařská fakulta Plzeň, Univerzita Karlova a Fakultnî nemocnice Plzeň

² Šiklův ústav patologie, Lékařská fakulta Plzeň, Univerzita Karlova a Fakultnî nemocnice Plzeň

³ Bioptická laboratoř, s. r. o., Plzeň

Khomenko K. Pivovarčíková K, Hora M, Pitra T. Nephrogenic adenoma of the bladder in renal transplant patient - case report. Nephrogenic adenoma (NA), also referred to as nephrogenic metaplasia, is a rare benign lesion affecting the urinary tract. The development of this lesion is attributed to the implantation of isolated renal tubular epithelial cells in areas of damaged transitional epithelium, often associated with prior instrumentation of the urinary tract. Clinical symptoms are nonspecific, commonly manifesting as hematuria (both macroscopic and microscopic), pollakisuria, and painful urination. Notably, during endoscopic examination, these lesions can be easily misinterpreted as malignant tumors. This publication presents two case reports of NA found in the urinary bladder of adult patients after kidney transplantation, the NAs faithfully mimicked urothelial carcinoma during cystoscopic and radiological examination.

Keywords: Case report, nephrogenic adenoma, transplantation.

Received: February 13, 2024; Revised: March 18, 2024; Accepted: March 25, 2024; Prepublished online: March 27, 2024; Published: May 2, 2024